It does support any game that TES5Edit (aka '圎dit') recognizes, but you will have to build and edit your own game settings to start.
For the average player, consider it 'experimental' at this time. Mator Smash is still in Alpha testing (buggy and 'unfinished' as to features, though basically functional) and only comes with initial settings for Skryrim at the moment. This document is a brief, unofficial guide to a program still in development.
3.3 Creating and building a new 'Smashed Patch'.3.2 Making an Automatic (Smash.All) Setting.
